Just as a PC needs code to operate, our bodies are managed by molecular “programs” that are coded earlier in life and then have to do their function correctly for the whole life. But do they work? It is a doubt that has haunted scientists for years.
Associate dean at the University of Miami Miller School of Medicine for therapeutic innovation and professor for behavioral sciences and psychiatry, Claes Wahlestedt, is the lead author of a new research posted in Aging Cell. The study is named as Longevity Related Molecular Pathways Are Subject to Midlife ‘Switch’ in Humans.
Collaborating with first author Jamie Timmons of Stirling University Science Park and King’s College London, United Kingdom, and a global group of scientists on human aging, Dr. Wahlestedt made an outstanding observation. Major molecular programs identified to promote longevity do not last more than midlife. The research offers a potential new factor why human disorder burden elevates so rapidly from the 6th decade of life onward as protective mechanisms for health vanish.
On a related note, aging people often show symptoms of slowing when it comes to handling their finances, such as balancing an account ledger or calculating their change when paying cash.
These modifications take place even in people who are cognitively fit. But the issue handling money can also be a forerunner of dementia and, as per new Duke study in The Journal of Prevention of Alzheimer’s Disease, can be associated to the degree of protein deposits gathered in the brain.
“There has been a misconception that fiscal difficulty might take place only in the late phases of dementia, but this can take place early and the modifications can be delicate,” claimed senior author of the paper and a professor at Duke for geriatrics and psychiatry, P. Murali Doraiswamy, to the media.
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